Microdosing, in the context articulated by Jamie Wheal, refers to the practice of consuming sub-perceptual amounts of psychedelic substances—such as LSD or psilocybin mushrooms—with the intention of enhancing cognitive function, emotional balance, and overall well-being without inducing the profound alterations in consciousness typically associated with full doses. This deliberate and mindful approach to psychopharmacology leverages the subtle biological and psychological effects of the compounds to promote creativity, clarity, and a heightened state of flow. By integrating microdoses into one’s routine, often on a structured schedule, individuals seek to harmonize their mental states, boost productivity, and attain a deeper connection to their purposeful endeavors, all while maintaining the functional equilibrium necessary for daily life.

See also: brain stem, serotonin system, altered state, flow genome project, microdose